Ontology highlight
ABSTRACT:
SUBMITTER: Nie Z
PROVIDER: S-EPMC3471363 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Nie Zuqin Z Hu Gangqing G Wei Gang G Cui Kairong K Yamane Arito A Resch Wolfgang W Wang Ruoning R Green Douglas R DR Tessarollo Lino L Casellas Rafael R Zhao Keji K Levens David D
Cell 20120901 1
The c-Myc HLH-bZIP protein has been implicated in physiological or pathological growth, proliferation, apoptosis, metabolism, and differentiation at the cellular, tissue, or organismal levels via regulation of numerous target genes. No principle yet unifies Myc action due partly to an incomplete inventory and functional accounting of Myc's targets. To observe Myc target expression and function in a system where Myc is temporally and physiologically regulated, the transcriptomes and the genome-wi ...[more]