Ontology highlight
ABSTRACT:
SUBMITTER: Cordova-Fletes C
PROVIDER: S-EPMC3473349 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Córdova-Fletes C C Domínguez M G MG Vázquez-Cárdenas A A Figuera L E LE Neira V A VA Rojas-Martínez A A Ortiz-López R R
Molecular syndromology 20120801 3
Cat-eye syndrome (CES) results from trisomy or tetrasomy of proximal 22q originated by a small supernumerary marker chromosome (sSMC). Two critical regions for the major clinical features of CES (CESCRs) have been suggested; however, CES clinical presentation often does not correlate with the sSMC genetic content. We report here a CES girl without coloboma and carrier of a de novo type I sSMC(22) as determined by G- and C-banding, NOR staining and microarrays. This sSMC included 6 distal genes o ...[more]