Genetic Susceptibility to Fungal Infections in Humans.
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ABSTRACT:
SUBMITTER: Lionakis MS
PROVIDER: S-EPMC3475324 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Publications
Genetic Susceptibility to Fungal Infections in Humans.
Current fungal infection reports 20111215 1
Most fungal infections in humans occur in the setting of iatrogenic immunosuppression or HIV infection. In the absence of these factors, fungi cause mild, self-limited infections that typically involve mucocutaneous surfaces. Hence, when persistent or recurrent mucocutaneous infections (chronic mucocutaneous candidiasis [CMC]) or invasive fungal infections (IFIs) develop in a "normal" host, they are indicative of genetic defects causing innate or adaptive immune dysfunction. In this review, rece ...[more]
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