Ontology highlight
ABSTRACT:
SUBMITTER: Arnold SE
PROVIDER: S-EPMC3478410 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Arnold Steven E SE Louneva Natalia N Cao Kajia K Wang Li-San LS Han Li-Ying LY Wolk David A DA Negash Selamawit S Leurgans Sue E SE Schneider Julie A JA Buchman Aron S AS Wilson Robert S RS Bennett David A DA
Neurobiology of aging 20120502 1
Although neuritic plaques and neurofibrillary tangles in older adults are correlated with cognitive impairment and severity of dementia, it has long been recognized that the relationship is imperfect, as some people exhibit normal cognition despite high levels of Alzheimer's disease (AD) pathology. We compared the cellular, synaptic, and biochemical composition of midfrontal cortices in female subjects from the Religious Orders Study who were stratified into three subgroups: (1) pathological AD ...[more]