Ontology highlight
ABSTRACT:
SUBMITTER: Sumigray KD
PROVIDER: S-EPMC3483132 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Sumigray Kaelyn D KD Foote Henry P HP Lechler Terry T
The Journal of cell biology 20121022 3
During differentiation, many cells reorganize their microtubule cytoskeleton into noncentrosomal arrays. Although these microtubules are likely organized to meet the physiological roles of their tissues, their functions in most cell types remain unexplored. In the epidermis, differentiation induces the reorganization of microtubules to cell-cell junctions in a desmosome-dependent manner. Here, we recapitulate the reorganization of microtubules in cultured epidermal cells. Using this reorganizati ...[more]