Ontology highlight
ABSTRACT:
SUBMITTER: Nguyen MT
PROVIDER: S-EPMC3483870 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Nguyen Minh-Thanh MT Zhu Jianjian J Nakamura Eiichiro E Bao Xiaozhong X Mackem Susan S
Developmental dynamics : an official publication of the American Association of Anatomists 20090201 2
The ability to generate conditional mutant alleles in mice using Cre-lox technology has facilitated analysis of genes playing critical roles in multiple developmental processes at different times. We used a transgenic Hoxb6 promoter to drive tamoxifen-dependent Cre recombinase expression in several developing systems that serve as major models for elucidating inductive interactions and mechanisms of morphogenesis, including lateral plate mesoderm and descendant limb buds, neural crest progenitor ...[more]