Ontology highlight
ABSTRACT:
SUBMITTER: Chen W
PROVIDER: S-EPMC3486865 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Chen Wentian W Zhong Yaogang Y Qin Yannan Y Sun Shisheng S Li Zheng Z
PloS one 20121101 11
Two glycoproteins, hemagglutinin (HA) and neuraminidase (NA), on the surface of influenza viruses play crucial roles in transfaunation, membrane fusion and the release of progeny virions. To explore the distribution of N-glycosylation sites (glycosites) in these two glycoproteins, we collected and aligned the amino acid sequences of all the HA and NA subtypes. Two glycosites were located at HA0 cleavage sites and fusion peptides and were strikingly conserved in all HA subtypes, while the remaini ...[more]