Ontology highlight
ABSTRACT:
SUBMITTER: Krauss M
PROVIDER: S-EPMC3486908 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Krauss Markus M Schaller Stephan S Borchers Steffen S Findeisen Rolf R Lippert Jörg J Kuepfer Lars L
PLoS computational biology 20121025 10
Cellular metabolism continuously processes an enormous range of external compounds into endogenous metabolites and is as such a key element in human physiology. The multifaceted physiological role of the metabolic network fulfilling the catalytic conversions can only be fully understood from a whole-body perspective where the causal interplay of the metabolic states of individual cells, the surrounding tissue and the whole organism are simultaneously considered. We here present an approach relyi ...[more]