Bioconjugation of green fluorescent protein via an unexpectedly stable cyclic sulfonium intermediate.
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ABSTRACT:
SUBMITTER: Nathani R
PROVIDER: S-EPMC3487180 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Publications
Bioconjugation of green fluorescent protein via an unexpectedly stable cyclic sulfonium intermediate.
Nathani Ramiz R Moody Paul P Smith Mark E B ME Fitzmaurice Richard J RJ Caddick Stephen S
Chembiochem : a European journal of chemical biology 20120525 9
Smooth converter: Bioconjugation of superfolder GFP involving the formation of an unusually stable, and unprecedented, cyclic sulfonium species is described. This sulfonium can undergo smooth reaction with a range of nucleophiles to give sulfur-, selenium- and azide-modified GFP derivatives in high conversions. ...[more]
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