Dataset Information

Factors that prolong the 'postmortem interval until finding' (PMI-f) among community-dwelling elderly individuals in Japan: analysis of registration data.

ABSTRACT:

Objectives

To clarify the factors affecting 'postmortem interval until finding' (PMI-f) among elderly unexpected death cases.

Design

Cross-sectional study.

Setting

All area of Yamagata prefecture in Japan.

Participants

Entering subjects were 5675 elderly cases with age of ?65 years selected from all 9002 cases of unexpected death from 2002 to 2007 in Yamagata prefecture between 2002 and 2007. Our final study subjects consisted of 3387 cases sampled with several criteria to assess the factors to prolong PMI-f.

Primary outcome measures

The outcome was the postmortem interval until finding (PMI-f) as the time from death until finding the body which we defined in this study.

Results

'Living alone' showed the highest adjusted HR (3.73, 95% CI 3.37 to 4.13), also 'unnatural death' (1.50, 1.28 to 1.75), 'found at own home' (1.37, 1.22 to 1.55) and 'younger subjects' (0.99, 0.98 to 0.99). In the model including interactions with the household situation, we found 'male subjects living alone' and 'female subjects living with family' tended to be found later.

Conclusions

PMI-f is an effective outcome for quantitative analyses of risk of bodies left. To prevent the elderly dead bodies left for long time, it is necessary to keep regular home-based contact with elderly individuals living alone.

SUBMITTER: Ito T

PROVIDER: S-EPMC3488755 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Factors that prolong the 'postmortem interval until finding' (PMI-f) among community-dwelling elderly individuals in Japan: analysis of registration data.

Ito Tomoko T Tamiya Nanako N Takahashi Hideto H Yamazaki Kentaro K Yamamoto Hideki H Sakano Shoji S Kashiwagi Masayo M Miyaishi Satoru S

BMJ open 20120927 5

<h4>Objectives</h4>To clarify the factors affecting 'postmortem interval until finding' (PMI-f) among elderly unexpected death cases.<h4>Design</h4>Cross-sectional study.<h4>Setting</h4>All area of Yamagata prefecture in Japan.<h4>Participants</h4>Entering subjects were 5675 elderly cases with age of ≥65 years selected from all 9002 cases of unexpected death from 2002 to 2007 in Yamagata prefecture between 2002 and 2007. Our final study subjects consisted of 3387 cases sampled with several crite ...[more]

PMID: 23024252

Similar Datasets

Project description:BackgroundPerinatal mortality may vary between herds, but the cost of deaths are always higher than value of the calf. When diagnosing the cause of a calf's death it is important to determine when it occurred, before or after calving. Metabolomics is widely used to identify many human diseases, but quite rarely applied in veterinary science. The aim of this study was to compare the metabolic profiles of calves with different times of death and those of calves born alive. Into the study, twenty one healthy controls (singleton, normal assisted calving, born alive) and 75 stillborn (SB) calves (with a gestation length of ?260?days, SB, or dead within 6?h of birth) were enrolled. Plasma and urine from SB and control calves were investigated by proton nuclear magnetic resonance based metabolomic methods. SB calves were divided into four PMI groups. One PMI group included calves that died after calving and the other groups - three comprised in utero deaths, based on pathophysiological changes (lung inflation, autolysis in internal organs, hemoglobin imbibition in the pleura and aortic arch). Partial Least Squares - Discriminant Analysis models based on plasma metabolites were calculated, reflecting assumed data clustering.ResultsTwenty six metabolites in plasma and 29 in urine changed significantly with PMI according to one way analysis of variance. Half the metabolites in plasma and the majority in urine increased with PMI. Six metabolites increased simultaneously in plasma and urine: acetate, sn-glycero-3-phosphocholine (GPC), leucine, valine, creatine, and alanine.ConclusionsPost-mortem changes in calves were associated with molecular variations in blood plasma and urine, showing the greatest differences for the group in which the post-mortem pathological changes were the most advanced. The results of the study show that evaluation of calf plasma or urine may be used as a diagnostic method for the determination of the PMI. Moreover, the metabolites, which unambiguously increased or decreased, can be used as potential biomarkers of PMI.

Dataset Information

Factors that prolong the 'postmortem interval until finding' (PMI-f) among community-dwelling elderly individuals in Japan: analysis of registration data.

Objectives

Design

Setting

Participants

Primary outcome measures

Results

Conclusions

Publications

Factors that prolong the 'postmortem interval until finding' (PMI-f) among community-dwelling elderly individuals in Japan: analysis of registration data.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets