Ontology highlight
ABSTRACT:
SUBMITTER: Litcofsky KD
PROVIDER: S-EPMC3492501 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Litcofsky Kevin D KD Afeyan Raffi B RB Krom Russell J RJ Khalil Ahmad S AS Collins James J JJ
Nature methods 20121007 11
We present a methodology for the design, construction and modification of synthetic gene networks. This method emphasizes post-assembly modification of constructs based on network behavior, thus facilitating iterative design strategies and rapid tuning and repurposing of gene networks. The ease of post-construction modification afforded by this approach and the ever-increasing repository of components within the framework will help accelerate the development of functional genetic circuits for sy ...[more]