Ontology highlight
ABSTRACT:
SUBMITTER: Bolduc KL
PROVIDER: S-EPMC3494784 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
Bolduc Kyle L KL Larsen Scott D SD Sherman David H DH
Chemical communications (Cambridge, England) 20120522
A flexible and divergent synthesis of cryptophycin unit A analogues is described. This method relies on iridium-catalysed stereo- and enantioselective crotylation and chemoselective one-pot oxidative olefination to access common intermediate . Heck, cross metathesis, and Suzuki-Miyaura reactions are illustrated for the generation of methyl ester unit A analogues . ...[more]