Ontology highlight
ABSTRACT:
SUBMITTER: Scherr N
PROVIDER: S-EPMC3497166 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Scherr Nicole N Röltgen Katharina K Witschel Matthias M Pluschke Gerd G
Antimicrobial agents and chemotherapy 20120924 12
An alamarBlue-based growth inhibition assay has been adapted for the thermosensitive and slow-growing pathogen Mycobacterium ulcerans. The standardized test procedure enables medium-throughput screening of preselected compound libraries. Testing of a set of 48 azoles with known antifungal activity led to the identification of an imidazole antifungal displaying an inhibitory dose (ID) of 9 μM for M. ulcerans. ...[more]