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CENP-A: the key player behind centromere identity, propagation, and kinetochore assembly.


ABSTRACT: Chromosome segregation is the one of the great problems in biology with complexities spanning from biophysics and polymer dynamics to epigenetics. Here, we summarize the current knowledge and highlight gaps in understanding of the mechanisms controlling epigenetic regulation of chromosome segregation.

SUBMITTER: De Rop V 

PROVIDER: S-EPMC3501172 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature

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CENP-A: the key player behind centromere identity, propagation, and kinetochore assembly.

De Rop Valérie V   Padeganeh Abbas A   Maddox Paul S PS  

Chromosoma 20121026 6


Chromosome segregation is the one of the great problems in biology with complexities spanning from biophysics and polymer dynamics to epigenetics. Here, we summarize the current knowledge and highlight gaps in understanding of the mechanisms controlling epigenetic regulation of chromosome segregation. ...[more]

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