Ontology highlight
ABSTRACT:
SUBMITTER: Jeffrey JL
PROVIDER: S-EPMC3503527 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Organic letters 20121012 21
Direct C(6) alkylation of pyridyl alcohols can be achieved following an initial deprotonation of the hydroxy group. This transformation, which is believed to occur by a Chichibabin-type alkylation, avoids lateral deprotonation prior to pyridine ring alkylation and gives increased regioselectivity for C(6) over C(4) alkylation. ...[more]