Ontology highlight
ABSTRACT:
SUBMITTER: Craig RA
PROVIDER: S-EPMC3506031 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Organic letters 20121026 22
A brief, enantioselective synthesis of a hydroxymethyl-cis-1,3-cyclopentenediol building block is presented. This scaffold allows access to the cis-1,3-cyclopentanediol fragments found in a variety of biologically active natural and non-natural products. This rapid and efficient synthesis is highlighted by the utilization of the palladium-catalyzed enantioselective allylic alkylation of dioxanone substrates to prepare tertiary alcohols. ...[more]