Dataset Information

TnpPred: A Web Service for the Robust Prediction of Prokaryotic Transposases.

ABSTRACT: Transposases (Tnps) are enzymes that participate in the movement of insertion sequences (ISs) within and between genomes. Genes that encode Tnps are amongst the most abundant and widely distributed genes in nature. However, they are difficult to predict bioinformatically and given the increasing availability of prokaryotic genomes and metagenomes, it is incumbent to develop rapid, high quality automatic annotation of ISs. This need prompted us to develop a web service, termed TnpPred for Tnp discovery. It provides better sensitivity and specificity for Tnp predictions than given by currently available programs as determined by ROC analysis. TnpPred should be useful for improving genome annotation. The TnpPred web service is freely available for noncommercial use.

SUBMITTER: Riadi G

PROVIDER: S-EPMC3506888 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature

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TnpPred: A Web Service for the Robust Prediction of Prokaryotic Transposases.

Riadi Gonzalo G Medina-Moenne Cristobal C Holmes David S DS

Comparative and functional genomics 20121118

Transposases (Tnps) are enzymes that participate in the movement of insertion sequences (ISs) within and between genomes. Genes that encode Tnps are amongst the most abundant and widely distributed genes in nature. However, they are difficult to predict bioinformatically and given the increasing availability of prokaryotic genomes and metagenomes, it is incumbent to develop rapid, high quality automatic annotation of ISs. This need prompted us to develop a web service, termed TnpPred for Tnp dis ...[more]

PMID: 23251097

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Dataset Information

TnpPred: A Web Service for the Robust Prediction of Prokaryotic Transposases.

Publications

TnpPred: A Web Service for the Robust Prediction of Prokaryotic Transposases.

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