Ontology highlight
ABSTRACT:
SUBMITTER: Gonnella G
PROVIDER: S-EPMC3507659 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Gonnella Giorgio G Kurtz Stefan S
BMC bioinformatics 20120506
<h4>Background</h4>Ongoing improvements in throughput of the next-generation sequencing technologies challenge the current generation of de novo sequence assemblers. Most recent sequence assemblers are based on the construction of a de Bruijn graph. An alternative framework of growing interest is the assembly string graph, not necessitating a division of the reads into k-mers, but requiring fast algorithms for the computation of suffix-prefix matches among all pairs of reads.<h4>Results</h4>Here ...[more]