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Asymmetric Bronsted acid-catalyzed aza-Diels-Alder reaction of cyclic C-acylimines with cyclopentadiene.

ABSTRACT: A new chiral Brønsted acid-catalyzed aza-Diels-Alder reaction of cyclic C-acylimines with cyclopentadiene has been developed. The reaction provides optically active aza-tetracycles in good yields with high diastereo- and enantioselectivities under mild reaction conditions.

SUBMITTER: Rueping M

PROVIDER: S-EPMC3511017 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature

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Asymmetric Brønsted acid-catalyzed aza-Diels-Alder reaction of cyclic C-acylimines with cyclopentadiene.

Rueping Magnus M Raja Sadiya S

Beilstein journal of organic chemistry 20121023

A new chiral Brønsted acid-catalyzed aza-Diels-Alder reaction of cyclic C-acylimines with cyclopentadiene has been developed. The reaction provides optically active aza-tetracycles in good yields with high diastereo- and enantioselectivities under mild reaction conditions. ...[more]

PMID: 23209517

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