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Asymmetric aza-Diels-Alder reaction of Danishefsky's diene with imines in a chiral reaction medium.

ABSTRACT: The asymmetric aza-Diels-Alder reaction of chiral imines with Danishefsky's diene in chiral ionic liquids provides the corresponding cycloadduct with moderate to high diastereoselectivity. The reaction has proved to perform better at room temperature in ionic liquids without either Lewis acid catalyst or organic solvent. Chiral ionic liquids are recycled while their efficiency is preserved.

SUBMITTER: Pegot B

PROVIDER: S-EPMC1592496 | biostudies-literature | 2006 Sep

REPOSITORIES: biostudies-literature

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Asymmetric aza-Diels-Alder reaction of Danishefsky's diene with imines in a chiral reaction medium.

Pégot Bruce B Nguyen Van Buu Olivier VB Gori Didier D Vo-Thanh Giang G

Beilstein journal of organic chemistry 20060918

The asymmetric aza-Diels-Alder reaction of chiral imines with Danishefsky's diene in chiral ionic liquids provides the corresponding cycloadduct with moderate to high diastereoselectivity. The reaction has proved to perform better at room temperature in ionic liquids without either Lewis acid catalyst or organic solvent. Chiral ionic liquids are recycled while their efficiency is preserved. ...[more]

PMID: 16982000

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