Mechanical and structural changes of the rat cervix in late-stage pregnancy.
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ABSTRACT:
SUBMITTER: Poellmann MJ
PROVIDER: S-EPMC3513513 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Publications
Mechanical and structural changes of the rat cervix in late-stage pregnancy.
Poellmann Michael J MJ Chien Edward K EK McFarlin Barbara L BL Wagoner Johnson Amy J AJ
Journal of the mechanical behavior of biomedical materials 20120820
Dysregulated remodeling of the cervix precedes preterm birth, a major cause of infant mortality and morbidity. The goal of this work was to identify changes in the mechanical properties of the cervix in late gestation. The tensile and load relaxation properties of cervices from rats 15-21 days (full term) post-conception were measured. Stiffness and load at 25% circumferential strain decreased with gestational age and correlated with the initial circumference of the cervix. Load-relaxation curve ...[more]
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