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Carbon nanotube-liposome supramolecular nanotrains for intelligent molecular-transport systems.

ABSTRACT: Biological network systems, such as inter- and intra-cellular signalling systems, are handled in a sophisticated manner by the transport of molecular information. Over the past few decades, there has been a growing interest in the development of synthetic molecular-transport systems. However, several key technologies have not been sufficiently realized to achieve optimum performance of transportation methods. Here we show that a new type of supramolecular system comprising of carbon nanotubes and liposomes enables the directional transport and controlled release of carrier molecules, and allows an enzymatic reaction at a desired area. The study highlights important progress that has been made towards the development of biomimetic molecular-transport systems and various lab-on-a-chip applications, such as medical diagnosis, sensors, bionic computers and artificial biological networks.

SUBMITTER: Miyako E

PROVIDER: S-EPMC3514502 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature

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Carbon nanotube-liposome supramolecular nanotrains for intelligent molecular-transport systems.

Miyako Eijiro E Kono Kenji K Yuba Eiji E Hosokawa Chie C Nagai Hidenori H Hagihara Yoshihisa Y

Nature communications 20120101

Biological network systems, such as inter- and intra-cellular signalling systems, are handled in a sophisticated manner by the transport of molecular information. Over the past few decades, there has been a growing interest in the development of synthetic molecular-transport systems. However, several key technologies have not been sufficiently realized to achieve optimum performance of transportation methods. Here we show that a new type of supramolecular system comprising of carbon nanotubes an ...[more]

PMID: 23187626

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