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4'-(4-Chloro-phen-yl)-3'-(4-meth-oxy-phen-yl)-3,4-dihydro-1H,4'H-spiro-[acridine-2,5'-isoxazol]-1-one.

ABSTRACT: In the title compound, C(28)H(21)ClN(2)O(3), the quinoline ring system is essentially planar with a maximum deviation of 0.0436?(17)?Å. The isoxazole and cyclo-hexane rings adopt envelope conformations. The isoxazole ring is almost orthogonal to both the quinoline ring system and the cyclo-hexane ring, making dihedral angles of 85.75?(8) and 81.46?(9) °, respectively. The O atom deviates signifigantly from the six-membered carbocyclic ring by 0.3947?(16)?Å. In the crystal, mol-ecules are linked into inversion dimers via pairs of C-H?O inter-actions, resulting in R(2) (2)(24) ring motifs.

SUBMITTER: Narayanan P

PROVIDER: S-EPMC3515270 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature

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4'-(4-Chloro-phen-yl)-3'-(4-meth-oxy-phen-yl)-3,4-dihydro-1H,4'H-spiro-[acridine-2,5'-isoxazol]-1-one.

Narayanan Ponmudisettu P Maheswari Shanmugavel Uma SU Sethusankar Krishnan K

Acta crystallographica. Section E, Structure reports online 20121020 Pt 11

In the title compound, C(28)H(21)ClN(2)O(3), the quinoline ring system is essentially planar with a maximum deviation of 0.0436 (17) Å. The isoxazole and cyclo-hexane rings adopt envelope conformations. The isoxazole ring is almost orthogonal to both the quinoline ring system and the cyclo-hexane ring, making dihedral angles of 85.75 (8) and 81.46 (9) °, respectively. The O atom deviates signifigantly from the six-membered carbocyclic ring by 0.3947 (16) Å. In the crystal, mol-ecules are linked ...[more]

PMID: 23284490

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