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Enantioselective total synthesis and studies into the configurational stability of bismurrayaquinone A.

ABSTRACT: Lost in rotation: the concise strategy of the first enantioselective total synthesis of bismurrayaquinone A utilized traceless stereochemical exchange to form an enantioenriched biphenyl core that was elaborated in a bidirectional manner to the natural product. Observed racemization on an unsuccessful initial route prompted studies into the configurational stability of bismurrayaquinone A and related biquinones.

SUBMITTER: Konkol LC

PROVIDER: S-EPMC3517045 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature

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Enantioselective total synthesis and studies into the configurational stability of bismurrayaquinone A.

Konkol Leah C LC Guo Fenghai F Sarjeant Amy A AA Thomson Regan J RJ

Angewandte Chemie (International ed. in English) 20110907 42

Lost in rotation: the concise strategy of the first enantioselective total synthesis of bismurrayaquinone A utilized traceless stereochemical exchange to form an enantioenriched biphenyl core that was elaborated in a bidirectional manner to the natural product. Observed racemization on an unsuccessful initial route prompted studies into the configurational stability of bismurrayaquinone A and related biquinones. ...[more]

PMID: 21898740

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