Ontology highlight
ABSTRACT:
SUBMITTER: Hayden CA
PROVIDER: S-EPMC3517206 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Plant biotechnology journal 20120721 8
Plant-based oral vaccines are a promising emergent technology that could help alleviate disease burden worldwide by providing a low-cost, heat-stable, oral alternative to parenterally administered commercial vaccines. Here, we describe high-level accumulation of the hepatitis B surface antigen (HBsAg) at a mean concentration of 0.51%TSP in maize T1 seeds using an improved version of the globulin1 promoter. This concentration is more than fourfold higher than any previously reported lines. HBsAg ...[more]