Liver X receptors and fat cell metabolism.
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ABSTRACT:
SUBMITTER: Laurencikiene J
PROVIDER: S-EPMC3520012 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Publications
Liver X receptors and fat cell metabolism.
International journal of obesity (2005) 20120228 12
Liver X receptors (LXRs) are members of the nuclear receptor family and are present in two isoforms, α and β, encoded by two separate genes. Originally described in the liver, LXRs have in the last 15 years been implicated in central metabolic pathways, including bile acid synthesis, lipid and glucose homeostasis. Although the vast majority of studies have been performed in non-adipose cells/tissues, results in recent years suggest that LXRs may have important modulatory roles in adipose tissue ...[more]
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