Ontology highlight
ABSTRACT:
SUBMITTER: Boshnjaku V
PROVIDER: S-EPMC3522071 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Scientific reports 20121214
Folic acid (FA) has traditionally been associated with prevention of neural tube defects; more recent work suggests that it may also be involved in in the prevention of adult onset diseases. As the role of FA in human health and disease expands, it also becomes more critical to understand the mechanisms behind FA action. In this work we examined the hypothesis that folate receptor alpha (FRα) acts as a transcription factor. FRα is a GPI-anchored protein and a component of the caveolae fraction. ...[more]