Ontology highlight
ABSTRACT:
SUBMITTER: Macura SL
PROVIDER: S-EPMC3524557 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Macura Sherrill L SL Hillegass Jedd M JM Steinbacher Jeremy L JL MacPherson Maximilian B MB Shukla Arti A Beuschel Stacie L SL Perkins Timothy N TN Butnor Kelly J KJ Lathrop Melissa J MJ Sayan Mutlay M Hekmatyar Khan K Taatjes Douglas J DJ Kauppinen Risto A RA Landry Christopher C CC Mossman Brooke T BT
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20120621 9
Pleural and peritoneal mesotheliomas (MMs) are chemoresistant tumors with no effective therapeutic strategies. The authors first injected multifunctional, acid-prepared mesoporous spheres (APMS), microparticles functionalized with tetraethylene glycol oligomers, intraperitoneally into rodents. Biodistribution of APMS was observed in major organs, peritoneal lavage fluid (PLF), and urine of normal mice and rats. After verification of increased mesothelin in human mesotheliomas injected into sever ...[more]