Ontology highlight
ABSTRACT:
SUBMITTER: Wu YC
PROVIDER: S-EPMC3526801 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Wu Yi-Chieh YC Rasmussen Matthew D MD Bansal Mukul S MS Kellis Manolis M
Systematic biology 20120904 1
Accurate gene tree reconstruction is a fundamental problem in phylogenetics, with many important applications. However, sequence data alone often lack enough information to confidently support one gene tree topology over many competing alternatives. Here, we present a novel framework for combining sequence data and species tree information, and we describe an implementation of this framework in TreeFix, a new phylogenetic program for improving gene tree reconstructions. Given a gene tree (prefer ...[more]