Ontology highlight
ABSTRACT:
SUBMITTER: Kaplun L
PROVIDER: S-EPMC3528110 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Kaplun Ludmila L Fridman Aviva Levine AL Chen Wei W Levin Nancy K NK Ahsan Sidra S Petrucelli Nancie N Barrick Jennifer L JL Gold Robin R Land Susan S Simon Michael S MS Morris Robert T RT Munkarah Adnan R AR Tainsky Michael A MA
Biomarker insights 20121212
A substantial fraction of familial ovarian cancer cases cannot be attributed to specific genetic factors. The discovery of additional susceptibility genes will permit a more accurate assessment of hereditary cancer risk and allow for monitoring of predisposed women in order to intervene at the earliest possible stage. We focused on a population with elevated familial breast and ovarian cancer risk. In this study, we identified a SNP rs926103 whose minor allele is associated with predisposition t ...[more]