Ontology highlight
ABSTRACT:
SUBMITTER: Kanduri M
PROVIDER: S-EPMC3528698 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Kanduri Meena M Marincevic Millaray M Halldórsdóttir Anna M AM Mansouri Larry L Junevik Katarina K Ntoufa Stavroula S Kultima Hanna Göransson HG Isaksson Anders A Juliusson Gunnar G Andersson Per-Ola PO Ehrencrona Hans H Stamatopoulos Kostas K Rosenquist Richard R
Epigenetics 20121115 12
Chronic lymphocytic leukemia (CLL) can be divided into prognostic subgroups based on the IGHV gene mutational status, and is further characterized by multiple subsets of cases with quasi-identical or stereotyped B cell receptors that also share clinical and biological features. We recently reported differential DNA methylation profiles in IGHV-mutated and IGHV-unmutated CLL subgroups. For the first time, we here explore the global methylation profiles of stereotyped subsets with different progno ...[more]