Ontology highlight
ABSTRACT:
SUBMITTER: Popkova A
PROVIDER: S-EPMC3531469 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Popkova Anna A Bernardoni Roberto R Diebold Celine C Van de Bor Véronique V Schuettengruber Bernd B González Inma I Busturia Ana A Cavalli Giacomo G Giangrande Angela A
PLoS genetics 20121227 12
The Gcm/Glide transcription factor is transiently expressed and required in the Drosophila nervous system. Threshold Gcm/Glide levels control the glial versus neuronal fate choice, and its perdurance triggers excessive gliogenesis, showing that its tight and dynamic regulation ensures the proper balance between neurons and glia. Here, we present a genetic screen for potential gcm/glide interactors and identify genes encoding chromatin factors of the Trithorax and of the Polycomb groups. These pr ...[more]