Ontology highlight
ABSTRACT:
SUBMITTER: Gao X
PROVIDER: S-EPMC3531553 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Gao Xiaoli X Zhang Qibin Q Meng Da D Isaac Giorgis G Zhao Rui R Fillmore Thomas L TL Chu Rosey K RK Zhou Jianying J Tang Keqi K Hu Zeping Z Moore Ronald J RJ Smith Richard D RD Katze Michael G MG Metz Thomas O TO
Analytical and bioanalytical chemistry 20120223 9
Lipidomics is a critical part of metabolomics and aims to study all the lipids within a living system. We present here the development and evaluation of a sensitive capillary UPLC-MS method for comprehensive top-down/bottom-up lipid profiling. Three different stationary phases were evaluated in terms of peak capacity, linearity, reproducibility, and limit of quantification (LOQ) using a mixture of lipid standards representative of the lipidome. The relative standard deviations of the retention t ...[more]