Ontology highlight
ABSTRACT:
SUBMITTER: Miyazaki T
PROVIDER: S-EPMC3535336 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Miyazaki Takamichi T Futaki Sugiko S Suemori Hirofumi H Taniguchi Yukimasa Y Yamada Masashi M Kawasaki Miwa M Hayashi Maria M Kumagai Hideaki H Nakatsuji Norio N Sekiguchi Kiyotoshi K Kawase Eihachiro E
Nature communications 20120101
Human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) have the potential to provide an infinite source of tissues for regenerative medicine. Although defined xeno-free media have been developed, culture conditions for reliable propagation of hESCs still require considerable improvement. Here we show that recombinant E8 fragments of laminin isoforms (LM-E8s), which are the minimum fragments conferring integrin-binding activity, promote greater adhesion of hESCs and hiPSCs ...[more]