Ontology highlight
ABSTRACT:
SUBMITTER: Polisetti N
PROVIDER: S-EPMC7338389 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Polisetti Naresh N Gießl Andreas A Li Shen S Sorokin Lydia L Kruse Friedrich E FE Schlötzer-Schrehardt Ursula U
Scientific reports 20200706 1
Limbal melanocytes, located in the basal epithelial layer of the corneoscleral limbus, represent essential components of the corneal epithelial stem cell niche, but, due to difficulties in their isolation and cultivation, their biological roles and potential for stem cell-based tissue engineering approaches have not been comprehensively studied. Here, we established a protocol for the efficient isolation and cultivation of pure populations of human limbal melanocytes, which could be expanded at ...[more]