Exceptional simian hemorrhagic fever virus diversity in a wild African primate community.
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ABSTRACT:
SUBMITTER: Lauck M
PROVIDER: S-EPMC3536393 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Publications
Exceptional simian hemorrhagic fever virus diversity in a wild African primate community.
Lauck Michael M Sibley Samuel D SD Hyeroba David D Tumukunde Alex A Weny Geoffrey G Chapman Colin A CA Ting Nelson N Switzer William M WM Kuhn Jens H JH Friedrich Thomas C TC O'Connor David H DH Goldberg Tony L TL
Journal of virology 20121017 1
Simian hemorrhagic fever virus (SHFV) is an arterivirus that causes severe disease in captive macaques. We describe two new SHFV variants subclinically infecting wild African red-tailed guenons (Cercopithecus ascanius). Both variants are highly divergent from the prototype virus and variants infecting sympatric red colobus (Procolobus rufomitratus). All known SHFV variants are monophyletic and share three open reading frames not present in other arteriviruses. Our data suggest a need to modify t ...[more]
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