Ontology highlight
ABSTRACT:
SUBMITTER: Peng Q
PROVIDER: S-EPMC3537242 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Protein science : a publication of the Protein Society 20120801 8
Synthetic/artificial protein switches provide an efficient means of controlling protein functions using chemical signals and stimuli. Mutually exclusive proteins, in which only the host or guest domain can remain folded at a given time owing to conformational strain, have been used to engineer novel protein switches that can switch enzymatic functions on and off in response to ligand binding. To further explore the potential of mutually exclusive proteins as protein switches and sensors, we repo ...[more]