Ontology highlight
ABSTRACT:
SUBMITTER: Wang LE
PROVIDER: S-EPMC3537906 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Wang Li-E LE Gorlova Olga Y OY Ying Jun J Qiao Yawei Y Weng Shih-Feng SF Lee Annette T AT Gregersen Peter K PK Spitz Margaret R MR Amos Christopher I CI Wei Qingyi Q
Cancer research 20121029 1
Suboptimal cellular DNA repair capacity (DRC) has been shown to be associated with enhanced cancer risk, but genetic variants affecting the DRC phenotype have not been comprehensively investigated. In this study, with the available DRC phenotype data, we analyzed correlations between the DRC phenotype and genotypes detected by the Illumina 317K platform in 1,774 individuals of European ancestry from a Texas lung cancer genome-wide association study. The discovery phase was followed by a replicat ...[more]