Ontology highlight
ABSTRACT:
SUBMITTER: Zhou Q
PROVIDER: S-EPMC3538135 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Zhou Qing Q Liu Ying Y Shin Dong-Sik DS Silangcruz Jaime J Tuleuova Nazgul N Revzin Alexander A
Langmuir : the ACS journal of surfaces and colloids 20120814 34
Aptamers have recently emerged as an excellent alternative to antibodies because of their inherent stability and ease of modification. In this paper, we describe the development of an aptamer-based surface for capture of cells expressing CD4 antigen. The glass or silicon surfaces were modified with amine-terminated silanes and then modified with thiolated RNA aptamer against CD4. Modification of the surface was first characterized by ellipsometry to demonstrate assembly of biointerface component ...[more]