Ontology highlight
ABSTRACT:
SUBMITTER: Takala-Harrison S
PROVIDER: S-EPMC3538248 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Takala-Harrison Shannon S Clark Taane G TG Jacob Christopher G CG Cummings Michael P MP Miotto Olivo O Dondorp Arjen M AM Fukuda Mark M MM Nosten Francois F Noedl Harald H Imwong Mallika M Bethell Delia D Se Youry Y Lon Chanthap C Tyner Stuart D SD Saunders David L DL Socheat Duong D Ariey Frederic F Phyo Aung Pyae AP Starzengruber Peter P Fuehrer Hans-Peter HP Swoboda Paul P Stepniewska Kasia K Flegg Jennifer J Arze Cesar C Cerqueira Gustavo C GC Silva Joana C JC Ricklefs Stacy M SM Porcella Stephen F SF Stephens Robert M RM Adams Matthew M Kenefic Leo J LJ Campino Susana S Auburn Sarah S MacInnis Bronwyn B Kwiatkowski Dominic P DP Su Xin-zhuan XZ White Nicholas J NJ Ringwald Pascal P Plowe Christopher V CV
Proceedings of the National Academy of Sciences of the United States of America 20121217 1
The recent emergence of artemisinin-resistant Plasmodium falciparum malaria in western Cambodia could threaten prospects for malaria elimination. Identification of the genetic basis of resistance would provide tools for molecular surveillance, aiding efforts to contain resistance. Clinical trials of artesunate efficacy were conducted in Bangladesh, in northwestern Thailand near the Myanmar border, and at two sites in western Cambodia. Parasites collected from trial participants were genotyped at ...[more]