Ontology highlight
ABSTRACT:
SUBMITTER: Zhu Y
PROVIDER: S-EPMC3546022 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Zhu Yumin Y Yu Xiaoming X Huang Fenfen F Yu Ruisong R Dong Shijuan S Si Fusheng F Zhang Yuanshu Y Li Zhen Z
Virology journal 20121108
<h4>Background</h4>Four major genotypes of hepatitis E virus (HEV), the causative agent of hepatitis E, have so far been recognized. While genotypes 3 and 4 are both zoonotic, the disease symptoms caused by the latter tend to be more severe. To examine if specific nucleotide/amino acid variations between genotypes 3 and 4 play a role in determining the severity of hepatitis E disease, the complete genome of one swine HEV genotype 4 isolate, SAAS-FX17, was determined and compared with other genot ...[more]