Ontology highlight
ABSTRACT:
SUBMITTER: Verweij KJ
PROVIDER: S-EPMC3548058 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Addiction biology 20120724 5
While initiation of cannabis use is around 40% heritable, not much is known about the underlying genetic aetiology. Here, we meta-analysed two genome-wide association studies of initiation of cannabis use with > 10 000 individuals. None of the genetic variants reached genome-wide significance. We also performed a gene-based association test, which also revealed no significant effects of individual genes. Finally, we estimated that only approximately 6% of the variation in cannabis initiation is ...[more]