Ontology highlight
ABSTRACT:
SUBMITTER: Lee JJ
PROVIDER: S-EPMC4159725 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Human genetics 20140418 8
The heritability of a trait (h(2)) is the proportion of its population variance caused by genetic differences, and estimates of this parameter are important for interpreting the results of genome-wide association studies (GWAS). In recent years, researchers have adopted a novel method for estimating a lower bound on heritability directly from GWAS data that uses realized genetic similarities between nominally unrelated individuals. The quantity estimated by this method is purported to be the con ...[more]