Ontology highlight
ABSTRACT:
SUBMITTER: Rish I
PROVIDER: S-EPMC3549920 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Rish Irina I Cecchi Guillermo G Thyreau Benjamin B Thirion Bertrand B Plaze Marion M Paillere-Martinot Marie Laure ML Martelli Catherine C Martinot Jean-Luc JL Poline Jean-Baptiste JB
PloS one 20130121 1
Schizophrenia is a psychiatric disorder that has eluded characterization in terms of local abnormalities of brain activity, and is hypothesized to affect the collective, "emergent" working of the brain. Indeed, several recent publications have demonstrated that functional networks in the schizophrenic brain display disrupted topological properties. However, is it possible to explain such abnormalities just by alteration of local activation patterns? This work suggests a negative answer to this q ...[more]