Ontology highlight
ABSTRACT:
SUBMITTER: Cebe P
PROVIDER: S-EPMC3553460 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Cebe Peggy P Hu Xiao X Kaplan David L DL Zhuravlev Evgeny E Wurm Andreas A Arbeiter Daniela D Schick Christoph C
Scientific reports 20130124
Beta-pleated-sheet crystals are among the most stable of protein secondary structures, and are responsible for the remarkable physical properties of many fibrous proteins, such as silk, or proteins forming plaques as in Alzheimer's disease. Previous thinking, and the accepted paradigm, was that beta-pleated-sheet crystals in the dry solid state were so stable they would not melt upon input of heat energy alone. Here we overturn that assumption and demonstrate that beta-pleated-sheet crystals mel ...[more]