Poly-?-(D)-glutamic acid capsule interferes with lytic infection of Bacillus anthracis by B. anthracis-specific bacteriophages.
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ABSTRACT:
SUBMITTER: Negus D
PROVIDER: S-EPMC3553781 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
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Poly-γ-(D)-glutamic acid capsule interferes with lytic infection of Bacillus anthracis by B. anthracis-specific bacteriophages.
Negus David D Burton Jane J Sweed Angela A Gryko Romuald R Taylor Peter W PW
Applied and environmental microbiology 20121102 2
The poly-γ-d-glutamic acid capsule of Bacillus anthracis is a barrier to infection by B. anthracis-specific bacteriophages. Capsule expression was found to completely inhibit lytic infection by γ phage, an observation supported by the demonstration that this phage does not elaborate a hydrolase that would facilitate penetration through the protective capsule outer layer. ...[more]
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