Ontology highlight
ABSTRACT:
SUBMITTER: Jiang H
PROVIDER: S-EPMC3555620 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Jiang Hua H Qiu Xusheng X Dai Jin J Yan Huang H Zhu Zezhang Z Qian Bangping B Qiu Yong Y
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 20121021 2
<h4>Purpose</h4>To investigate whether rs11190870 near LBX1 correlates with the susceptibility or curve progression of adolescent idiopathic scoliosis (AIS) in a Han Chinese population.<h4>Methods</h4>A total of 949 AIS patients and 976 age-matched healthy controls were recruited. All the subjects were genotyped using the PCR-based invader assay. Case-control study and case-only study were performed to define the contribution of rs11190870 to predisposition and curve severity of AIS. Additionall ...[more]