Ontology highlight
ABSTRACT:
SUBMITTER: Bales KL
PROVIDER: S-EPMC3556198 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Bales Karen L KL Perkeybile Allison M AM Conley Olivia G OG Lee Meredith H MH Guoynes Caleigh D CD Downing Griffin M GM Yun Catherine R CR Solomon Marjorie M Jacob Suma S Mendoza Sally P SP
Biological psychiatry 20121016 3
<h4>Background</h4>Oxytocin (OT) is a hormone shown to be involved in social bonding in animal models. Intranasal OT is currently in clinical trials for use in disorders such as autism and schizophrenia. We examined long-term effects of intranasal OT given developmentally in the prairie vole (Microtus ochrogaster), a socially monogamous rodent, often used as an animal model to screen drugs that have therapeutic potential for social disorders.<h4>Methods</h4>We treated voles with one of three dos ...[more]