Ontology highlight
ABSTRACT:
SUBMITTER: Wang H
PROVIDER: S-EPMC3703824 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Wang Hui H Duclot Florian F Liu Yan Y Wang Zuoxin Z Kabbaj Mohamed M
Nature neuroscience 20130602 7
In the socially monogamous prairie vole (Microtus ochrogaster), mating induces enduring pair-bonds that are initiated by partner preference formation and regulated by a variety of neurotransmitters, including oxytocin, vasopressin and dopamine. We examined potential epigenetic mechanisms mediating pair-bond regulation and found that the histone deacetylase inhibitors sodium butyrate and trichostatin A (TSA) facilitated partner preference formation in female prairie voles in the absence of mating ...[more]