Atomoxetine increases fronto-parietal functional MRI activation in attention-deficit/hyperactivity disorder: a pilot study.
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ABSTRACT:
SUBMITTER: Bush G
PROVIDER: S-EPMC3557757 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
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Atomoxetine increases fronto-parietal functional MRI activation in attention-deficit/hyperactivity disorder: a pilot study.
Bush George G Holmes Jennifer J Shin Lisa M LM Surman Craig C Makris Nikos N Mick Eric E Seidman Larry J LJ Biederman Joseph J
Psychiatry research 20121110 1
We hypothesized that atomoxetine (ATMX) would produce similar brain effects in attention-deficit/hyperactivity disorder (ADHD) as those of methylphenidate (MPH). Eleven ADHD adults performed the Multi-Source Interference Task (MSIT) during functional magnetic resonance imaging (fMRI) at baseline and after 6 weeks of ATMX treatment. ATMX was associated with increased fMRI activation of dorsolateral prefrontal cortex, parietal cortex and cerebellum but not dorsal anterior midcingulate cortex (daMC ...[more]
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